The documentary begins with a brief overview of Dr. John's life and career, from his early days as a session musician to his iconic public persona as the "Night Tripper." The film then transitions into a series of musical performances, each one a tribute to Dr. John's diverse musical influences and genres.

The performances range from soulful renditions of blues classics to funky grooves that reflect the essence of New Orleans music. The documentary also features interviews with the participating musicians, who share their personal reflections and experiences with Dr. John's music.

One of the highlights of the film is the collaboration between Dr. John's former band and contemporary musicians, who forces to play some of his most well-known songs. The movie also showcases Dr. John's own performances, which showcase his incredible stage presence and musical virtuosity.

Despite the documentary's celebratory tone, it also dives into some of Dr. John's most difficult moments, including his struggles with addiction and the impact it had on his life and career. The film explores how Dr. John's personal struggles and triumphs are reflected in his music, culminating in a moving tribute to the late musician.

Overall, "Various Artists - The Musical Mojo of Dr. John: A Celebration of Mac & His Music" is an engaging and heartfelt tribute to one of the most influential musicians of our time. Whether you are a die-hard fan or new to Dr. John's music, this documentary is a must-see for anyone who appreciates the power of music to inspire and unite people from all walks of life.